What do Chronic GI Distress and Neuropathic pain have in common?

Patients with life-threatening hereditary transthyretin amyloidosis (hATTR) often present with a cluster of 2, 3, or more seemingly unrelated red-flag symptoms, including bilateral carpal tunnel syndrome, heart failure, neuropathic pain, and chronic GI distress.1,2

Other symptoms that can make up the cluster include alternating diarrhea and constipation, orthostatic hypotension, sexual dysfunction, and renal abnormalities.1,2

In life-threatening hATTR amyloidosis, hope starts with diagnosis.1

The symptoms of hATTR amyloidosis
How to test for hATTR amyloidosis